Catalog

Azides

Azide Modification. If you require this modification, please contact us info@genterra.ru

Terminal azide is a functional group, which can be incorporated into oligonucleotide internally or at 5’- and 3’-ends. Alkyne oligonucleotides can be conjugated with aдлнту-containing labels/tags (e.g., fluorescent dyes, biotin, or oligos) with high regioselectivity and efficiency using “Click Chemistry” (a [3+2] cycloaddition in presence of copper (I) ions or in Strain promoted “Click Chemistry”).

Available sites for modifications are 5’, internal and 3’.